About reboxetine mesilate
Selective norepinephrine reuptake inhibitor
Used for
- Treatment of major depressive disorder.
Usual adult dose
Usually 4 mg twice daily; may increase to 10 mg daily after 3 weeks if needed and tolerated.
Common side effects
- Dry mouth
- Constipation
- Insomnia
- Increased sweating
Important warnings
- May increase blood pressure or heart rate.
- Can worsen urinary retention or glaucoma.
- Rarely, depression treatment may increase suicidal thoughts, especially early on.
- Stopping suddenly may cause withdrawal symptoms; dose reduction is usually gradual.
Pregnancy
Use during pregnancy only when a clinician judges benefits outweigh potential risks; information is limited.
Breastfeeding
Information is limited; use requires clinical assessment of benefits and potential risks.
Interactions
- Monoamine oxidase inhibitors can cause serious reactions; avoid combined use.
- Other medicines that raise serotonin may increase serotonin syndrome risk.
- Strong CYP3A4 inhibitors can increase reboxetine levels.
- Medicines affecting blood pressure or heart rhythm may increase adverse effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.