About cholic acid
Primary bile acid
Used for
- Treats certain rare bile acid synthesis disorders
- Treats Zellweger spectrum disorders with impaired bile acid synthesis
Usual adult dose
Usually 5–15 mg/kg once daily, adjusted by a specialist; may be divided into two doses.
Usual dose in children
Usually 5–15 mg/kg once daily, adjusted by a specialist; may be divided into two doses.
Common side effects
- Diarrhea
- Nausea
- Reflux or vomiting
- Abnormal liver tests
Important warnings
- Specialist supervision and regular liver tests are required.
- Dose may need adjustment based on liver tests and bile acid levels.
- Not suitable for all causes of liver disease.
- Swallow capsules whole; follow product instructions if a child cannot swallow them.
Pregnancy
Use only if the specialist considers treatment necessary; pregnancy data are limited.
Breastfeeding
It is unknown whether cholic acid passes into breast milk; specialist advice is needed.
Interactions
- Bile acid-binding medicines, such as cholestyramine, can reduce absorption.
- Some antacids containing aluminium may reduce absorption.
- Cyclosporine may affect cholic acid levels.
- Discuss other medicines with the treating specialist.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.