About trimethop rim
Antibiotic; dihydrofolate reductase inhibitor
Used for
- Treats certain bacterial urinary infections
- May be used for other susceptible bacterial infections
Usual adult dose
Common urinary infection dose: 200 mg twice daily, usually for 3–10 days; depends on infection.
Usual dose in children
For children over 3 months: usually 4 mg/kg twice daily; dose and duration depend on infection.
Common side effects
- Nausea or vomiting
- Rash or itching
- Diarrhea
- Raised potassium or blood-cell changes
Important warnings
- Not suitable for some blood disorders or folate deficiency.
- Kidney problems may require dose adjustment.
- Seek urgent care for severe rash, mouth sores, or breathing difficulty.
- Trimethoprim alone is not appropriate for every bacterial infection.
Pregnancy
Use in pregnancy only when a clinician considers it necessary; it may affect folate, especially early in pregnancy.
Breastfeeding
Usually compatible with breastfeeding a healthy, full-term infant; seek advice for premature or jaundiced infants.
Interactions
- Warfarin: may increase bleeding risk.
- Methotrexate: increased toxicity risk.
- Phenytoin: may increase phenytoin levels.
- ACE inhibitors, ARBs, or spironolactone: increased potassium risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.