About hydroxytryptophan
Serotonin precursor supplement
Used for
- Marketed for mood support, sleep, and migraine prevention; evidence is limited and mixed.
Usual adult dose
Supplement doses vary; commonly 50–100 mg once or twice daily. No established dose for these uses.
Common side effects
- Nausea
- Diarrhea
- Drowsiness
- Headache
Important warnings
- Can cause serotonin syndrome, especially with medicines that increase serotonin.
- Supplement quality and actual contents may vary.
- Avoid with carbidopa unless directed by a clinician; severe reactions have been reported.
Pregnancy
Safety is not established; use is generally avoided during pregnancy.
Breastfeeding
Safety is not established; use is generally avoided while breastfeeding.
Interactions
- Antidepressants, tramadol, triptans, and other serotonin-raising medicines: serotonin syndrome risk.
- Carbidopa: may increase risk of serious adverse effects.
- Sedatives and alcohol: may increase drowsiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.