About melphalan
Alkylating chemotherapy medicine
Used for
- Treats multiple myeloma.
- Treats certain ovarian cancers.
- Used for some other cancers under specialist care.
Usual adult dose
Varies by cancer and treatment plan; prescribed and monitored by a cancer specialist.
Usual dose in children
Specialist-determined; use in children is uncommon and depends on the cancer.
Common side effects
- Low blood counts, increasing infection or bleeding risk.
- Nausea, vomiting, or diarrhea.
- Mouth sores.
- Hair loss or infertility.
Important warnings
- Can cause severe bone marrow suppression and serious infections.
- Requires regular blood-count monitoring and dose adjustment.
- May cause infertility and increase risk of later cancers.
- Handle tablets carefully; avoid exposure if pregnant.
Pregnancy
Can harm an unborn baby. Avoid during pregnancy; effective contraception is required during treatment and afterward as directed.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential serious harm to the infant.
Interactions
- Other medicines that suppress bone marrow can increase blood-related risks.
- Live vaccines may cause infection during treatment.
- Cyclosporine may increase kidney injury risk, especially with high-dose melphalan.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.