About tobramycin
Aminoglycoside antibiotic
Used for
- Treats chronic lung infection with Pseudomonas aeruginosa in cystic fibrosis.
Usual adult dose
For cystic fibrosis: inhale one dose twice daily for 28 days, then stop for 28 days; repeat cycles.
Usual dose in children
For cystic fibrosis, generally the same twice-daily, 28-days-on and 28-days-off schedule; use is typically for ages six and older.
Common side effects
- Cough, hoarse voice, or altered taste
- Breathlessness or wheezing
- Sore throat
- Ringing in the ears or hearing changes
Important warnings
- Can cause bronchospasm; lung function may worsen after inhalation.
- May affect hearing, balance, or kidney function, especially with other toxic medicines.
- Use only with a suitable nebuliser; do not swallow or mix with other medicines.
- Not generally recommended for people with cystic fibrosis who have certain severe kidney or hearing problems.
Pregnancy
Use during pregnancy only when clearly needed; potential fetal harm is uncertain.
Breastfeeding
Small amounts may enter breast milk; infant absorption is expected to be low, but discuss with a clinician.
Interactions
- Other medicines that can harm kidneys or hearing, including aminoglycoside antibiotics
- Loop diuretics such as furosemide
- Neuromuscular-blocking medicines
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.