About buprenorphine hydrochloride
Partial opioid agonist
Used for
- Treats opioid use disorder as part of a supervised treatment program.
Usual adult dose
Usually started at 2–4 mg under the tongue; adjusted gradually, commonly to 8–16 mg daily.
Common side effects
- Constipation, nausea, headache, sweating
- Sleepiness, dizziness, or faintness
- Withdrawal symptoms, especially if started too soon
- Slow or difficult breathing
Important warnings
- Can cause fatal breathing problems, especially with alcohol, sedatives, or other opioids.
- Use only as prescribed; swallowing tablets reduces effectiveness.
- Stopping suddenly can cause withdrawal; seek supervised dose changes.
- Keep securely stored: accidental exposure can seriously harm children.
Pregnancy
Use during pregnancy only under medical supervision. Untreated opioid use disorder also carries serious risks; newborn withdrawal may occur.
Breastfeeding
Buprenorphine can pass into breast milk. Discuss use with a clinician and monitor the baby for unusual sleepiness or breathing problems.
Interactions
- Alcohol, benzodiazepines, and other sedatives increase breathing and overdose risks.
- Other opioids may increase sedation or cause withdrawal when buprenorphine is started.
- Some antifungals, antibiotics, and HIV medicines can alter buprenorphine levels.
- Rifampin and some seizure medicines may reduce its effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.