About Septrin Tablets
Antibiotic combination
Used for
- Certain urinary, respiratory, and ear infections
- Pneumocystis pneumonia treatment or prevention
- Some other susceptible bacterial infections
Usual adult dose
Common infections: 160 mg trimethoprim/800 mg sulfamethoxazole every 12 hours; dose and duration vary by infection.
Usual dose in children
For children over two months, dosing is weight-based and depends on the infection; younger infants should not receive it.
Common side effects
- Nausea, vomiting, or loss of appetite
- Rash or itching
- Increased potassium or changes in blood counts
- Rare severe skin reactions
Important warnings
- Avoid with sulfonamide or trimethoprim allergy.
- Rarely causes severe skin reactions, blood disorders, or serious organ injury.
- Use caution with kidney or liver disease, folate deficiency, or high potassium.
- Not for infants younger than two months.
Pregnancy
Can affect folate metabolism; use during pregnancy only when the expected benefit outweighs risks, especially near delivery.
Breastfeeding
Usually compatible for healthy, full-term infants; avoid or seek specialist advice if the infant is premature, jaundiced, ill, or G6PD-deficient.
Interactions
- Warfarin: increased bleeding risk
- Methotrexate: increased toxicity
- ACE inhibitors or spironolactone: increased potassium
- Phenytoin: increased drug levels
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.