About felbamate
Antiseizure medication
Used for
- Treatment of certain severe seizures, including Lennox–Gastaut syndrome.
- Add-on treatment for partial seizures when other medicines are inadequate.
Usual adult dose
Usually starts at 1,200 mg daily in divided doses; adjusted gradually by a specialist.
Usual dose in children
For Lennox–Gastaut syndrome, usually starts at 15 mg/kg daily in divided doses; adjusted gradually by a specialist.
Common side effects
- Nausea, vomiting, or reduced appetite
- Headache, dizziness, or sleepiness
- Weight loss or trouble sleeping
Important warnings
- Rare but potentially fatal aplastic anemia and liver failure; blood tests and liver monitoring are required.
- Use is generally restricted to severe epilepsy when benefits outweigh serious risks.
- Do not stop suddenly; seizures may worsen.
- Report unusual bruising, bleeding, infection, severe fatigue, or yellow skin promptly.
Pregnancy
Pregnancy data are limited. Seizures and treatment risks require specialist review; do not stop suddenly.
Breastfeeding
Information is limited. Felbamate may enter breast milk; monitor the infant for sleepiness or poor feeding.
Interactions
- Can lower blood levels of hormonal contraceptives, potentially reducing effectiveness.
- Can increase phenytoin levels and side effects.
- Can lower levels of carbamazepine and valproate.
- Alcohol and sedating medicines may worsen drowsiness or dizziness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.