About pimavanserin
Atypical antipsychotic; serotonin inverse agonist
Used for
- Treats hallucinations and delusions associated with Parkinson’s disease psychosis.
Usual adult dose
34 mg by mouth once daily, with or without food.
Common side effects
- Swelling of the arms or legs
- Nausea
- Confusion
- Constipation
Important warnings
- Can increase the risk of death in older adults with dementia-related psychosis; not approved for this use.
- May prolong the heart’s electrical rhythm, increasing risk of serious irregular heartbeat.
- Can cause confusion or sleepiness and increase fall risk.
- Do not stop or change treatment without medical guidance.
Pregnancy
Human pregnancy data are limited; use only when potential benefits justify potential risks.
Breastfeeding
It is unknown whether pimavanserin passes into breast milk; breastfeeding is not recommended during treatment.
Interactions
- Strong CYP3A4 inhibitors can increase pimavanserin levels; dose reduction is needed.
- Strong or moderate CYP3A4 inducers can reduce levels and should be avoided.
- Other medicines that prolong the QT interval can increase heart-rhythm risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.