About amikacin sulfate
Aminoglycoside antibiotic
Used for
- Treats serious infections caused by susceptible bacteria, including some resistant infections.
- May be used for certain urinary, abdominal, blood, or bone infections.
Usual adult dose
Usually 15 mg/kg per day by injection, once daily or divided; dosing is adjusted for kidney function and infection.
Usual dose in children
Usually 15–20 mg/kg per day by injection, once daily or divided; dosing is adjusted for age, kidney function, and infection.
Common side effects
- Kidney damage
- Hearing or balance problems, sometimes permanent
- Nausea or rash
- Pain at the injection site
Important warnings
- Requires medical supervision and often blood-level, kidney, and hearing monitoring.
- Risk of kidney and hearing damage rises with high doses, prolonged treatment, or kidney impairment.
- Use only for bacterial infections; resistance can make treatment ineffective.
- Seek urgent care for breathing difficulty or severe allergic reaction.
Pregnancy
May harm the developing baby’s hearing; use during pregnancy only when clearly necessary.
Breastfeeding
Small amounts may enter milk; infant absorption is expected to be low, but monitor for diarrhea or thrush.
Interactions
- Other kidney- or hearing-damaging medicines, including cisplatin, vancomycin, and some diuretics, increase toxicity risk.
- Neuromuscular blockers and some anesthetics may increase muscle weakness or breathing problems.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.