About loxoprofen sodium
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Short-term relief of pain and inflammation
- Osteoarthritis, rheumatoid arthritis, and low back pain
- Pain after surgery, injury, or tooth extraction
- Fever and pain from acute upper respiratory infections
Usual adult dose
Usually 60 mg by mouth three times daily; for fever or pain, 60 mg as needed, up to three times daily. Follow local prescribing guidance.
Common side effects
- Stomach pain, indigestion, nausea, or diarrhea
- Dizziness or headache
- Fluid retention or raised blood pressure
- Rash or abnormal liver or kidney tests
Important warnings
- Can cause stomach ulcers, bleeding, or perforation, sometimes without warning.
- May increase heart attack or stroke risk, especially with prolonged use.
- Avoid with aspirin-sensitive asthma or active stomach ulcer; use caution with kidney, liver, or heart disease.
- Use the lowest effective dose for the shortest time; avoid combining with other NSAIDs.
Pregnancy
Avoid from 20 weeks unless specifically directed; do not use from 30 weeks or during labor.
Breastfeeding
Use only if a clinician considers it necessary; safety information is limited.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including aspirin, increase stomach and kidney risks.
- ACE inhibitors, ARBs, and diuretics may worsen kidney function or blood pressure control.
- Lithium or methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.