About clobazam
Benzodiazepine antiseizure medicine
Used for
- Add-on treatment for seizures in Lennox–Gastaut syndrome
- Sometimes used for other seizure disorders
Usual adult dose
For Lennox–Gastaut syndrome, usually 5–40 mg daily, adjusted gradually and divided once or twice daily.
Usual dose in children
For Lennox–Gastaut syndrome, children aged 2 years and older: usually 5–40 mg daily, based on weight and divided once or twice daily.
Common side effects
- Sleepiness and tiredness
- Dizziness or unsteadiness
- Drooling
- Constipation or nausea
Important warnings
- Can cause dependence and withdrawal; reduce gradually, not suddenly.
- May slow breathing, especially with opioids, alcohol, or other sedatives.
- Can impair alertness and coordination; avoid driving if affected.
- Seek urgent care for severe rash, facial swelling, or breathing difficulty.
Pregnancy
May harm an unborn baby, particularly late in pregnancy; use requires careful specialist assessment.
Breastfeeding
Clobazam passes into breast milk and may cause infant sleepiness or poor feeding; specialist assessment is needed.
Interactions
- Opioids, alcohol, and sedatives increase drowsiness and breathing risk.
- Cannabidiol can increase clobazam effects and sleepiness.
- Some medicines, including fluconazole, can raise clobazam levels.
- Carbamazepine and phenytoin can alter clobazam levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.