About tianeptine
Atypical antidepressant
Used for
- Treatment of major depressive episodes
Usual adult dose
Usually 12.5 mg three times daily before meals; lower doses may be used in older adults or severe kidney disease.
Common side effects
- Nausea, stomach pain, constipation, dry mouth
- Dizziness, headache, drowsiness, weakness
- Sleep problems, tremor, sweating
- Rarely, liver problems or severe allergic reactions
Important warnings
- Can cause dependence and misuse; avoid increasing doses or prolonged unsupervised use.
- Do not stop suddenly; withdrawal symptoms can occur, so reduce gradually with medical guidance.
- Avoid alcohol; use caution with driving if drowsy or dizzy.
- Do not use with monoamine oxidase inhibitors; allow the prescribed washout period.
Pregnancy
Use only when a clinician considers it necessary; discuss risks and benefits, especially near delivery.
Breastfeeding
Breastfeeding is generally not recommended during treatment; discuss alternatives with a clinician.
Interactions
- Monoamine oxidase inhibitors can cause serious reactions; avoid concurrent use.
- Alcohol may increase drowsiness and other nervous-system effects.
- Other sedating medicines may increase drowsiness or impaired coordination.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.