About aminocaproic acid
Antifibrinolytic medicine
Used for
- Helps control bleeding when blood clots break down too quickly.
- Used for certain surgical, dental, or medical bleeding episodes.
Usual adult dose
Commonly 5 g initially, then 1–1.25 g hourly or 5 g every 3–6 hours; dosing varies by condition.
Usual dose in children
Usually 100 mg/kg initially, then 33 mg/kg hourly; maximum 5 g per dose. Specialist-directed dosing is required.
Common side effects
- Nausea, vomiting, or diarrhea
- Dizziness or headache
- Low blood pressure
- Muscle weakness or pain
Important warnings
- Can cause dangerous clots; use only when excessive clot breakdown is confirmed or suspected.
- Avoid in active intravascular clotting; use caution with kidney impairment or blood in urine.
- Longer treatment may require monitoring for muscle injury and blood clots.
- Seek urgent care for chest pain, breathlessness, one-sided swelling, or sudden weakness.
Pregnancy
Use only when clearly needed; human pregnancy safety information is limited.
Breastfeeding
Information is limited; use with medical guidance.
Interactions
- Factor IX complex concentrates or anti-inhibitor coagulant concentrates may increase clot risk.
- Estrogen-containing contraceptives may increase clot risk.
- Thrombolytic medicines such as alteplase may have reduced effect.
- Avoid combining with other clot-promoting medicines unless specifically directed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.