About deferasiro x
Oral iron-chelating medicine
Used for
- Treats chronic iron overload from repeated blood transfusions.
- Treats chronic iron overload in some non-transfusion-dependent blood disorders.
Usual adult dose
Usually 14 mg/kg once daily for transfusion-related overload; 7 mg/kg once daily for non-transfusion-dependent overload. Specialist-adjusted.
Usual dose in children
Used in children aged 2 years and older; dose is weight-based and specialist-adjusted.
Common side effects
- Nausea, vomiting, diarrhoea, or abdominal pain
- Skin rash
- Raised liver enzymes
- Changes in kidney tests
Important warnings
- Can cause serious kidney, liver, or gastrointestinal bleeding problems.
- Kidney, liver, blood counts, and iron levels require regular monitoring.
- Avoid during severe kidney or liver disease; dose changes may be needed.
- Seek urgent assessment for black stools, severe abdominal pain, or reduced urination.
Pregnancy
Pregnancy data are limited; use only when clearly necessary after specialist assessment.
Breastfeeding
It is unknown whether deferasirox passes into breast milk; breastfeeding is generally not recommended during treatment.
Interactions
- Antacids containing aluminium can affect treatment; avoid taking them together.
- May increase effects of medicines such as repaglinide or theophylline.
- Medicines that increase bleeding risk, such as anticoagulants, may raise gastrointestinal bleeding risk.
- Other medicines that can harm the kidneys may increase kidney injury risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.