About sildenafil citrate
Phosphodiesterase-5 inhibitor
Used for
- Erectile dysfunction
- Pulmonary arterial hypertension
Usual adult dose
Erectile dysfunction: usually 50 mg as needed, up to once daily. Pulmonary arterial hypertension dosing differs by product.
Usual dose in children
Pulmonary arterial hypertension: specialist-directed dosing; not for routine use in children.
Common side effects
- Headache
- Flushing
- Indigestion
- Changes in vision
Important warnings
- Never combine with nitrate medicines or riociguat; blood pressure may fall dangerously.
- Seek urgent care for an erection lasting over four hours or sudden vision or hearing loss.
- Use caution with heart disease, low blood pressure, or medicines that lower blood pressure.
- Do not take more than once daily for erectile dysfunction.
Pregnancy
Not indicated for erectile dysfunction in pregnancy. Use for pulmonary hypertension only under specialist direction.
Breastfeeding
Not generally used during breastfeeding; treatment for pulmonary hypertension requires specialist assessment.
Interactions
- Nitrates, including nitroglycerin, can cause severe blood-pressure drops.
- Riociguat is contraindicated with sildenafil.
- Some antibiotics, antifungals, and HIV medicines can increase sildenafil levels.
- Alpha-blockers and other blood-pressure medicines may increase dizziness or fainting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.