About cefotaxime
Third-generation cephalosporin antibiotic
Used for
- Treats serious bacterial infections, including pneumonia and blood infections.
- Treats meningitis, urinary infections, and infections of the abdomen or skin.
Usual adult dose
Usually 1–2 g by injection every 8–12 hours; severe infections may need higher, more frequent doses.
Usual dose in children
Usually 50–150 mg/kg/day by injection, divided every 6–12 hours; meningitis may require higher doses.
Common side effects
- Diarrhea, nausea, or vomiting
- Injection-site pain or inflammation
- Rash or allergic reaction
- Changes in blood counts or liver tests
Important warnings
- Use only for bacterial infections; it does not treat viral illnesses.
- Serious allergy can occur, especially with previous cephalosporin reactions.
- Dose may need adjustment in kidney impairment.
- Antibiotic-associated severe diarrhea can occur during or after treatment.
Pregnancy
May be used when clinically needed; pregnancy safety evidence is limited.
Breastfeeding
Small amounts may enter breast milk; infant diarrhea or thrush is possible.
Interactions
- Probenecid can increase cefotaxime levels.
- Other medicines that can harm the kidneys may increase kidney-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.