About metoclopramide hcl
Dopamine-blocking antiemetic and prokinetic
Used for
- Treats nausea and vomiting
- Short-term treatment of reflux symptoms
- Helps stomach emptying in diabetic gastroparesis
Usual adult dose
Usually 10 mg up to four times daily; dose and duration depend on the condition.
Usual dose in children
For selected uses, 0.1–0.15 mg/kg per dose up to three times daily; specialist guidance is needed.
Common side effects
- Drowsiness or tiredness
- Restlessness or diarrhea
- Involuntary movements, which can persist
- Raised prolactin levels
Important warnings
- Use the shortest effective course; prolonged use increases movement-disorder risk.
- Avoid with bowel blockage, bleeding, or perforation.
- May cause sleepiness; avoid driving if affected.
- Dose reduction may be needed with kidney problems.
Pregnancy
May be used when clinically needed; treatment near delivery can affect the newborn.
Breastfeeding
Passes into breast milk; possible effects on the infant and milk supply require consideration.
Interactions
- Antipsychotics increase movement-related side effects.
- Levodopa and dopamine medicines may work less effectively.
- Alcohol and sedatives can increase drowsiness.
- Some antidepressants increase side effects or serotonin-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.