About diclofenac sodium
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation in arthritis and other joint conditions
- Short-term treatment of painful sprains, strains, and other musculoskeletal conditions
- Relief of menstrual pain
Usual adult dose
Usually 50 mg two or three times daily, depending on the condition; use the lowest effective dose for the shortest time.
Usual dose in children
For juvenile arthritis, dosing is weight-based and prescribed by a clinician; not for routine use in children.
Common side effects
- Indigestion, nausea, or stomach pain
- Diarrhea or headache
- Stomach ulcer or bleeding
- Fluid retention or raised blood pressure
Important warnings
- May increase the risk of heart attack or stroke, especially with prolonged use or high doses.
- Can cause serious stomach bleeding or ulcers; risk is higher in older adults.
- Avoid with active stomach ulcers, severe heart, kidney, or liver disease, or NSAID allergy.
- Do not combine with other NSAIDs unless specifically directed.
Pregnancy
Avoid from 20 weeks unless specifically prescribed; contraindicated during the last trimester because of fetal and delivery risks.
Breastfeeding
Small amounts may enter breast milk; short-term use is generally considered compatible, but seek clinician guidance.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including ibuprofen and naproxen, increase side effects.
- ACE inhibitors, ARBs, and diuretics may have reduced effects and increased kidney risks.
- Lithium, methotrexate, and digoxin levels may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.