About bexarotene
Retinoid X receptor agonist
Used for
- Treats skin lesions of cutaneous T-cell lymphoma after other treatments have not worked.
Usual adult dose
Usually 300 mg/m² once daily with a meal; specialist may adjust the dose.
Common side effects
- High blood fats
- Low thyroid hormone
- Headache
- Skin rash or itching
Important warnings
- Can cause severe birth defects; pregnancy must be avoided during treatment.
- Requires monitoring of blood fats, liver function, blood counts, and thyroid function.
- May cause pancreatitis or liver problems.
- Avoid donating blood during treatment and for one month afterward.
Pregnancy
Do not use during pregnancy; it can cause severe birth defects.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Gemfibrozil can increase bexarotene levels.
- Vitamin A supplements may increase toxicity.
- Some medicines can reduce its effectiveness, including rifampin and phenytoin.
- Bexarotene may reduce hormonal contraceptive effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.