About zuclopenthixol acetate
Short-acting first-generation antipsychotic
Used for
- Short-term control of severe agitation or psychosis in schizophrenia and other psychotic disorders
Usual adult dose
Usually 50–150 mg by deep intramuscular injection; may be repeated after 2–3 days. Treatment is generally limited to a few injections.
Common side effects
- Drowsiness or dizziness
- Movement problems, including stiffness, tremor, or restlessness
- Dry mouth, constipation, or blurred vision
- Low blood pressure
Important warnings
- Can cause severe movement reactions, including a rare, life-threatening muscle reaction.
- May increase risk of abnormal heart rhythm, especially with heart disease or interacting medicines.
- Use caution with seizures, liver disease, and older adults with dementia-related psychosis.
- The oily injection is for deep intramuscular use only.
Pregnancy
Use only when clearly needed; antipsychotic exposure late in pregnancy may cause newborn movement or withdrawal symptoms.
Breastfeeding
May pass into breast milk; potential infant effects should be considered.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness.
- Medicines that prolong QT interval can increase abnormal heart rhythm risk.
- Levodopa and dopamine agonists may have reduced effects.
- Other antipsychotics or medicines affecting blood pressure may increase adverse effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.