About Septrin Double Strength Tablets
Sulfonamide antibiotic combination
Used for
- Urinary tract infections
- Certain respiratory infections, including Pneumocystis pneumonia
- Shigellosis and some other bacterial infections
Usual adult dose
For many infections, one tablet by mouth every 12 hours; dose and duration depend on infection and kidney function.
Usual dose in children
For selected infections, dosing is based on weight and divided every 12 hours; not suitable for all children.
Common side effects
- Nausea, vomiting, or loss of appetite
- Rash and itching
- Increased potassium or changes in blood counts
- Rarely, severe skin reactions or liver problems
Important warnings
- Not effective against viral infections.
- Avoid with sulfonamide or trimethoprim allergy; serious reactions can occur.
- Kidney impairment, folate deficiency, and older age may increase risks.
- Seek urgent care for blistering rash, breathing difficulty, or unusual bruising.
Pregnancy
Use is generally avoided, especially near delivery; use earlier in pregnancy only when benefits outweigh risks.
Breastfeeding
Small amounts enter breast milk. Caution is advised for premature, jaundiced, or ill infants and infants with G6PD deficiency.
Interactions
- Warfarin: may increase bleeding risk.
- Methotrexate: may increase toxicity.
- ACE inhibitors or spironolactone: may increase potassium.
- Phenytoin: may increase phenytoin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.