About loperamid e hcl
Antidiarrheal opioid-receptor agonist
Used for
- Short-term relief of acute diarrhea
- Control of chronic diarrhea under medical supervision
- Reducing stool output in ileostomy patients
Usual adult dose
Acute diarrhea: 4 mg initially, then 2 mg after each loose stool; maximum 16 mg daily. Follow local package directions.
Usual dose in children
Children aged 2–12 years: dose depends on age and weight; use only with professional guidance. Not for children under 2.
Common side effects
- Constipation
- Nausea
- Abdominal cramps
- Dizziness or drowsiness
Important warnings
- Do not use with bloody stools, high fever, or suspected bacterial diarrhea.
- Stop and seek medical care if diarrhea lasts over 48 hours or worsens.
- Excess doses can cause life-threatening heart rhythm problems.
- Avoid use with severe constipation or abdominal swelling.
Pregnancy
Use only when needed after discussing risks with a healthcare professional; avoid self-treatment.
Breastfeeding
Small amounts may enter breast milk; ask a healthcare professional before use.
Interactions
- Quinidine, ritonavir, or gemfibrozil may increase loperamide levels.
- Drugs that prolong QT intervals may increase risk of dangerous heart rhythms.
- Other medicines that slow bowel movement may increase constipation risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.