About ethacrynate sodium
Loop diuretic
Used for
- Treats fluid retention (edema), including with heart failure, liver disease, or kidney disease.
- May be used to treat high blood pressure.
Usual adult dose
Usually 50–200 mg by mouth once daily; doses are individualized and may be adjusted.
Usual dose in children
Usually 1–2 mg/kg by mouth once daily; specialist-directed dosing is required.
Common side effects
- Frequent urination, dizziness, or low blood pressure.
- Dehydration and low potassium or other electrolytes.
- Nausea, diarrhea, or stomach discomfort.
- Hearing changes, especially with high doses or kidney problems.
Important warnings
- Can cause dehydration, electrolyte abnormalities, or worsening kidney function.
- Seek prompt assessment for ringing in the ears or hearing loss.
- Caution with gout, diabetes, liver disease, or severe kidney disease.
- Monitoring of kidney function and blood electrolytes may be needed.
Pregnancy
Use only when clearly needed; risks and benefits should be assessed by a clinician.
Breastfeeding
Information is limited; it may reduce milk production. Discuss use with a clinician.
Interactions
- Other medicines that can harm hearing, such as aminoglycoside antibiotics.
- Lithium; diuretics can increase lithium levels.
- Digoxin; low potassium can increase risk of toxicity.
- NSAIDs, which may reduce its diuretic effect and affect kidney function.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.