About estrogens
Conjugated estrogen hormone therapy
Used for
- Treats moderate to severe menopausal hot flashes and vaginal symptoms.
- Prevents osteoporosis after menopause when other options are unsuitable.
- Treats low estrogen levels due to ovarian failure or removal.
- Used with a progestogen for certain menstrual disorders.
Usual adult dose
Usually 0.3–1.25 mg once daily; dose and schedule depend on the condition.
Common side effects
- Breast tenderness, headache, nausea, or abdominal discomfort.
- Vaginal bleeding or spotting, especially when starting treatment.
- Fluid retention or mood changes.
- Skin reactions or changes in libido.
Important warnings
- Can increase risks of blood clots, stroke, and certain cancers.
- Unopposed estrogen increases endometrial cancer risk in people with a uterus.
- Not for preventing heart disease or dementia.
- Regular review is important; use the lowest effective dose for the shortest necessary time.
Pregnancy
Not used during pregnancy; stop if pregnancy occurs.
Breastfeeding
May reduce milk production; generally avoided while breastfeeding.
Interactions
- Some seizure medicines, rifampin, and St John’s wort may reduce estrogen effects.
- Estrogen can affect thyroid replacement requirements and some blood-thinning medicines.
- Certain medicines may increase estrogen levels or side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.