About aripiprazo le
Atypical antipsychotic
Used for
- Schizophrenia
- Bipolar I disorder
- Add-on treatment for major depressive disorder
- Irritability associated with autism
Usual adult dose
Usually 10–15 mg once daily for schizophrenia or bipolar disorder; 2–5 mg daily initially when added for depression.
Usual dose in children
For schizophrenia or bipolar disorder, usually 2 mg daily initially, increased gradually; approved age and target dose depend on condition.
Common side effects
- Restlessness or difficulty sitting still
- Nausea or vomiting
- Headache
- Sleepiness or insomnia
Important warnings
- May increase blood sugar, cholesterol, and weight.
- Can cause uncontrollable movements or compulsive gambling and shopping.
- Older adults with dementia-related psychosis have increased risk of death.
- May cause dizziness or fainting, especially when standing.
Pregnancy
Use during pregnancy only when the expected benefit outweighs potential risks; late-pregnancy exposure may cause newborn movement or feeding problems.
Breastfeeding
Aripiprazole may reduce milk supply and passes into breast milk; infant exposure and feeding should be monitored.
Interactions
- Strong CYP2D6 or CYP3A4 inhibitors can increase aripiprazole levels.
- Strong CYP3A4 inducers can lower aripiprazole levels.
- Alcohol and medicines causing sleepiness may increase impairment.
- Medicines affecting blood pressure may increase dizziness or fainting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.