About amphotericin b
Liposomal polyene antifungal
Used for
- Serious fungal infections, including invasive aspergillosis and candidiasis
- Cryptococcal meningitis, often with other antifungal medicines
- Visceral leishmaniasis
Usual adult dose
Usually 3–5 mg/kg by intravenous infusion once daily; dose and duration depend on infection.
Usual dose in children
Usually 3–5 mg/kg by intravenous infusion once daily; dose and duration depend on infection.
Common side effects
- Fever, chills, nausea, or vomiting during infusion
- Low potassium or magnesium
- Kidney problems
- Anemia
Important warnings
- Given by intravenous infusion under medical supervision.
- Kidney function, blood counts, and potassium and magnesium require monitoring.
- Infusion reactions can be serious; allergic reactions are possible.
- This liposomal product is not interchangeable with other amphotericin B formulations.
Pregnancy
Use only when the infection requires treatment; available information is limited, and the clinician weighs benefits and risks.
Breastfeeding
Information is limited; discuss use with a clinician, especially when nursing a newborn or premature infant.
Interactions
- Other kidney-harming medicines may increase kidney injury risk.
- Medicines that lower potassium may increase low-potassium risk.
- Some cancer medicines can increase kidney or blood-cell effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.