About Grofenac Suppositories
Nonsteroidal anti-inflammatory drug
Used for
- Pain and inflammation from arthritis
- Muscle and joint pain
- Pain after surgery
- Period pain
Usual adult dose
Rectally, 75–150 mg daily in divided doses. Maximum 150 mg daily, including diclofenac taken by other routes.
Usual dose in children
For juvenile arthritis: 1–3 mg/kg daily in divided doses, using suitable pediatric formulations under specialist supervision.
Common side effects
- Stomach pain, nausea, or indigestion
- Diarrhea
- Headache or dizziness
- Rectal irritation
Important warnings
- May cause stomach ulcers or bleeding, even when used rectally.
- May increase heart attack, stroke, and kidney damage risk.
- Avoid with previous aspirin or NSAID allergic reactions.
- Avoid with rectal bleeding or inflammation.
Pregnancy
Avoid from 20 weeks unless specifically prescribed; do not use from 30 weeks because of fetal kidney and heart risks.
Breastfeeding
Passes into breast milk in very small amounts; generally considered compatible with breastfeeding.
Interactions
- Other NSAIDs or aspirin increase bleeding and ulcer risk.
- Blood thinners, corticosteroids, and some antidepressants increase bleeding risk.
- Diuretics and certain blood pressure medicines increase kidney damage risk.
- May increase lithium and methotrexate toxicity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.