About aripiprazole
Atypical antipsychotic
Used for
- Schizophrenia
- Bipolar I disorder, including manic episodes
- Add-on treatment for major depressive disorder
- Irritability associated with autistic disorder
Usual adult dose
Usually 10–15 mg once daily for schizophrenia or bipolar mania; doses vary by condition and response.
Usual dose in children
For schizophrenia, ages 13–17: usually 10 mg once daily. For bipolar mania, ages 10–17: usually 10 mg once daily.
Common side effects
- Restlessness or difficulty sitting still
- Nausea, vomiting, or constipation
- Headache or dizziness
- Sleepiness or insomnia
Important warnings
- Can increase blood sugar, cholesterol, or weight.
- May cause compulsive gambling, shopping, eating, or sexual urges.
- Can cause movement problems, including tardive dyskinesia.
- Increased risk of death in older adults with dementia-related psychosis.
Pregnancy
Use during pregnancy only when the expected benefit outweighs potential risks; late-pregnancy exposure may cause newborn movement or feeding problems.
Breastfeeding
Aripiprazole may reduce milk supply and can pass into breast milk; infant effects are possible.
Interactions
- Strong CYP2D6 or CYP3A4 inhibitors can increase aripiprazole levels.
- Strong CYP3A4 inducers can lower aripiprazole levels.
- May increase the effects of blood-pressure-lowering medicines.
- Alcohol and sedating medicines can worsen drowsiness or impaired coordination.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.