About Bupivacaine Injection BP (0.5%
W/V)
Long-acting local anaesthetic
Used for
- Local or regional anaesthesia for surgery
- Epidural anaesthesia and pain relief
- Nerve blocks
Usual adult dose
Varies by procedure and route; clinicians use the lowest effective dose, commonly up to 150 mg per procedure.
Usual dose in children
Weight-based and procedure-specific; administered by trained clinicians, with doses carefully limited.
Common side effects
- Low blood pressure
- Nausea or vomiting
- Numbness, dizziness, or ringing in the ears
- Rarely, seizures or dangerous heart rhythm problems
Important warnings
- Must be administered by trained clinicians with monitoring and resuscitation equipment available.
- Accidental injection into a blood vessel can cause seizures or cardiac arrest.
- Dose depends on route, procedure, patient factors, and other local anaesthetics.
- Use extra caution with heart, liver, or kidney problems.
Pregnancy
May be used when clinically needed; epidural use during childbirth is established. Use depends on clinical assessment.
Breastfeeding
Generally compatible with breastfeeding when used locally or for epidural anaesthesia; transfer into milk is expected to be low.
Interactions
- Other local anaesthetics can increase toxic effects.
- Anti-arrhythmia medicines may increase heart-related side effects.
- Medicines affecting liver enzymes may alter bupivacaine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.