About secretin
Gastrointestinal peptide hormone
Used for
- Stimulates pancreatic secretions during diagnostic testing of pancreatic function.
- Helps diagnose gastrinoma using a secretin stimulation test.
- Assesses pancreatic and biliary ducts during endoscopic testing.
Usual adult dose
Dose depends on the diagnostic test; commonly 0.2 micrograms/kg intravenously for pancreatic testing or 0.4 micrograms/kg for gastrinoma testing.
Usual dose in children
Not routinely used in children; dosing is specialist-directed.
Common side effects
- Nausea or vomiting
- Abdominal discomfort or cramping
- Flushing
- Changes in blood pressure or heart rate
Important warnings
- Use only for supervised diagnostic procedures.
- Allergic reactions, including severe reactions, can occur.
- Can affect blood pressure and heart rate.
- Follow test-specific preparation and monitoring instructions.
Pregnancy
Human pregnancy data are limited; use only when the diagnostic benefit justifies potential risk.
Breastfeeding
It is unknown whether secretin enters breast milk; clinical data are limited.
Interactions
- Anticholinergic medicines may reduce secretin-stimulated pancreatic secretions.
- Some medicines affecting gastric acid secretion may alter test results.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.