About bicalutamide
Nonsteroidal antiandrogen
Used for
- Treatment of prostate cancer, usually with other hormone therapy.
- Sometimes used alone for locally advanced prostate cancer.
Usual adult dose
50 mg once daily with hormone therapy; 150 mg once daily when used alone for locally advanced disease.
Common side effects
- Hot flashes
- Breast tenderness or enlargement
- Nausea
- Liver problems
Important warnings
- Can cause serious liver injury; liver tests may be needed.
- Not for use by women or children.
- May harm a developing fetus; avoid handling crushed tablets during pregnancy.
- Seek urgent care for yellow skin, dark urine, or severe abdominal pain.
Pregnancy
Contraindicated; may cause fetal harm.
Breastfeeding
Not indicated for women; breastfeeding safety is not established.
Interactions
- Warfarin and related blood thinners: may increase bleeding risk.
- Some medicines that affect liver enzymes can alter bicalutamide levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.