About diclofenac sodium + suppository
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation, including arthritis and musculoskeletal conditions
- Short-term treatment of acute pain, such as after surgery
Usual adult dose
Usually 75–150 mg daily in divided doses; rectal use is generally once daily, sometimes twice daily, within this total.
Common side effects
- Stomach pain, indigestion, nausea, or diarrhea
- Rectal irritation or discomfort
- Headache or dizziness
- Fluid retention or increased blood pressure
Important warnings
- Can cause stomach ulcers, bleeding, or perforation, sometimes without warning.
- May increase the risk of heart attack or stroke, especially with prolonged use.
- Avoid with active stomach ulcers, severe heart failure, or aspirin-sensitive asthma.
- Use the lowest effective dose for the shortest necessary time.
Pregnancy
Avoid from 20 weeks unless specifically directed; contraindicated from 30 weeks because of fetal risks.
Breastfeeding
Generally not recommended; diclofenac use should be reviewed with a healthcare professional, particularly for repeated doses.
Interactions
- Blood thinners and antiplatelet medicines can increase bleeding risk.
- Other NSAIDs, including ibuprofen, increase side-effect risks.
- ACE inhibitors, ARBs, and diuretics may affect kidney function or blood pressure.
- Lithium, methotrexate, and digoxin levels may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.