About irbesartan
Angiotensin II receptor blocker
Used for
- High blood pressure
- Kidney protection in adults with type 2 diabetes and high blood pressure
Usual adult dose
Usually 150 mg once daily for high blood pressure; 300 mg once daily may be used. For diabetic kidney disease, usually 300 mg once daily.
Usual dose in children
Not established for children under 6. Ages 6–16: usually 75 mg once daily; doses vary by weight and response.
Common side effects
- Dizziness
- Fatigue
- Nausea
- High potassium levels
Important warnings
- Can cause dangerously low blood pressure, especially with dehydration.
- May impair kidney function or raise potassium; monitoring may be needed.
- Do not use during pregnancy; stop promptly if pregnancy occurs.
- Avoid aliskiren in people with diabetes; avoid combining with ACE inhibitors unless directed.
Pregnancy
Can harm or kill a developing baby, particularly later in pregnancy. Avoid; discontinue promptly if pregnancy occurs.
Breastfeeding
Limited information is available, especially for newborn or premature infants. Discuss suitable alternatives with a clinician.
Interactions
- Aliskiren, ACE inhibitors, or other blood-pressure medicines may increase risks.
- Potassium supplements and potassium-sparing diuretics can raise potassium.
- NSAIDs, including ibuprofen, may worsen kidney function and reduce blood-pressure control.
- Lithium levels may rise, increasing toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.