About bezafibrate
Fibrate lipid-lowering medicine
Used for
- Lowers high triglycerides and cholesterol when diet and other measures are insufficient.
- May be used for mixed lipid disorders or severe hypertriglyceridaemia.
Usual adult dose
Usually 400 mg once daily with food for sustained-release tablets; dose depends on kidney function.
Common side effects
- Stomach upset, nausea, or diarrhoea.
- Muscle pain or weakness; rarely, muscle breakdown.
- Raised liver enzymes or skin rash.
- Gallstones.
Important warnings
- Kidney impairment may require a lower dose or avoidance.
- Seek prompt assessment for unexplained muscle pain, tenderness, or weakness.
- Liver and kidney function may need monitoring.
- Not suitable for some gallbladder or severe liver disorders.
Pregnancy
Generally avoid during pregnancy; safety information is limited.
Breastfeeding
Use is generally not recommended during breastfeeding.
Interactions
- Statins and other medicines that can damage muscle increase muscle-injury risk.
- Warfarin effects may increase; closer monitoring may be needed.
- Some diabetes medicines may increase glucose-lowering effects.
- Immunosuppressants such as ciclosporin may increase kidney-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.