About Tekozol 200mg Tablets
Oral antifungal medicine
Used for
- Historically treated serious fungal infections when safer treatments were unsuitable.
- Oral tablets are no longer recommended for routine fungal infections.
Usual adult dose
Historically, 200 mg once daily; specialist-directed increases were sometimes used.
Common side effects
- Nausea, vomiting, and abdominal pain
- Liver injury, sometimes severe or fatal
- Adrenal hormone suppression
- Rash and itching
Important warnings
- Can cause severe liver damage; treatment requires careful monitoring.
- May suppress adrenal function, especially during illness or surgery.
- Many medicines interact; some combinations can cause dangerous heart rhythm problems.
- Oral ketoconazole is restricted in many countries because of serious risks.
Pregnancy
Avoid unless a specialist determines it is essential; pregnancy safety is uncertain.
Breastfeeding
Generally avoid; discuss alternatives with a healthcare professional.
Interactions
- Do not combine with certain medicines affecting heart rhythm, including some antiarrhythmics.
- Acid-reducing medicines can lower ketoconazole absorption.
- Strong enzyme-inducing medicines, such as rifampicin, can reduce its effect.
- Ketoconazole can raise levels of many medicines, including some statins and sedatives.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.