About itraconazole
Triazole antifungal
Used for
- Oral thrush and esophageal candidiasis
- Prevention of fungal infections in some people with weakened immunity
Usual adult dose
Oral thrush: 200 mg once daily for 1–2 weeks. Esophageal candidiasis: 100 mg daily for at least 3 weeks.
Common side effects
- Nausea, diarrhea, or abdominal pain
- Headache or dizziness
- Liver enzyme changes
- Rash
Important warnings
- Can cause serious liver injury; stop and seek medical care for jaundice or dark urine.
- May worsen heart failure; avoid for nail infections in people with heart failure.
- Many medicines interact; some combinations can cause dangerous heart rhythm problems.
- The oral solution is not interchangeable with itraconazole capsules; take solution on an empty stomach.
Pregnancy
Avoid during pregnancy unless treating a serious infection and benefits outweigh risks. Do not use for nail infections during pregnancy.
Breastfeeding
Small amounts may enter breast milk; discuss use with a clinician, especially for prolonged treatment.
Interactions
- Some statins, sedatives, and heart-rhythm medicines can reach dangerous levels.
- Rifampin, rifabutin, and some seizure medicines can reduce itraconazole levels.
- Acid-reducing medicines may affect itraconazole absorption; effects differ by formulation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.