About sugammadex sodium salt sugammadex
Selective neuromuscular blockade reversal agent
Used for
- Reverses rocuronium- or vecuronium-induced muscle relaxation after surgery.
Usual adult dose
Usually 2 mg/kg or 4 mg/kg intravenously, depending on blockade depth; 16 mg/kg for immediate reversal after rocuronium.
Usual dose in children
For children aged 2 years and older: usually 2 mg/kg intravenously after rocuronium or vecuronium; other situations may require specialist dosing.
Common side effects
- Nausea
- Vomiting
- Pain
- Slow heart rate
Important warnings
- Can cause severe allergic reactions, including anaphylaxis.
- May cause marked slowing of the heart rate, rarely cardiac arrest.
- Use caution with severe kidney impairment; it is generally not recommended.
- Hormonal contraceptives may be less effective after treatment.
Pregnancy
Human pregnancy data are limited; use only when clinically necessary.
Breastfeeding
Unknown whether it passes into breast milk; effects on infants are uncertain.
Interactions
- May reduce hormonal contraceptive effectiveness; follow missed-pill guidance for seven days.
- Toremifene may prolong sugammadex exposure and affect reversal.
- Some medicines, including fusidic acid, may delay recovery of muscle function.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.