About chlorphen iramine maleate
First-generation antihistamine
Used for
- Relief of allergic reactions, including hives, itching, and allergic rhinitis
- Adjunctive treatment of severe allergic reactions, alongside emergency treatments
Usual adult dose
For allergic reactions: 10–20 mg by slow injection; repeat if needed, maximum 40 mg in 24 hours.
Usual dose in children
Children aged 1 month–1 year: 250 micrograms/kg; 1–5 years: 2.5–5 mg; 6–12 years: 5–10 mg. Repeat every 4–6 hours if needed, maximum 2 mg/kg or 40 mg daily, whichever is lower.
Common side effects
- Drowsiness, dizziness, and impaired coordination
- Dry mouth, blurred vision, or constipation
- Nausea or difficulty urinating
Important warnings
- Can cause marked sleepiness; avoid driving if affected.
- Use cautiously with glaucoma, breathing problems, or difficulty urinating.
- Slow intravenous administration is required; rapid injection can cause low blood pressure.
- Not a substitute for adrenaline in anaphylaxis.
Pregnancy
Use only when needed after professional assessment; safety information is limited, particularly early in pregnancy.
Breastfeeding
May cause infant drowsiness or irritability and may reduce milk supply; seek professional advice before use.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness.
- Monoamine oxidase inhibitors can intensify anticholinergic effects.
- Other medicines causing drowsiness or dry mouth may increase these effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.