About fidaxomicin
Macrocyclic antibiotic
Used for
- Treats Clostridioides difficile infection (C. difficile diarrhoea) in adults and children aged six months or older.
Usual adult dose
200 mg by mouth twice daily for 10 days.
Usual dose in children
For ages 6 months to under 18 years: dose depends on weight and formulation, twice daily for 10 days. Tablets are for children able to swallow them.
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Constipation
Important warnings
- Not suitable for infections other than C. difficile diarrhoea.
- Seek urgent care for signs of a severe allergic reaction.
- Use cautiously in severe kidney or liver problems; experience is limited.
Pregnancy
Human pregnancy data are limited. Use only when a clinician considers it necessary.
Breastfeeding
It is unknown whether fidaxomicin passes into breast milk; discuss use with a clinician.
Interactions
- Ciclosporin may increase fidaxomicin levels; monitor for side effects.
- Strong P-glycoprotein inhibitors, such as ketoconazole, may increase fidaxomicin exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.