About apixaban
Direct oral factor Xa inhibitor
Used for
- Prevents stroke and blood clots in adults with certain heart rhythm problems.
- Treats deep vein thrombosis and pulmonary embolism.
- Prevents recurrent blood clots after treatment.
- Prevents blood clots after hip or knee replacement surgery.
Usual adult dose
Usually 5 mg twice daily for atrial fibrillation or initial clot treatment; 2.5 mg twice daily for selected prevention uses. Treatment regimens vary.
Common side effects
- Bleeding or bruising
- Anemia
- Nausea
- Rash
Important warnings
- Can cause serious or fatal bleeding.
- Do not stop without medical guidance; stopping can raise clot risk.
- Spinal or epidural procedures can cause serious bleeding around the spine.
- Kidney or liver problems may affect safety and dosing.
Pregnancy
Use only when clearly needed; pregnancy safety information is limited, and bleeding risk requires clinical assessment.
Breastfeeding
It is not known whether apixaban passes into breast milk; discuss feeding options with a clinician.
Interactions
- Other blood thinners, aspirin, and NSAIDs increase bleeding risk.
- Strong CYP3A4 or P-glycoprotein inhibitors can raise apixaban levels.
- Strong CYP3A4 or P-glycoprotein inducers can lower apixaban levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.