About human hepatitis b immunoglobulin
Human hepatitis B immunoglobulin
Used for
- Prevention of hepatitis B after exposure, including needlestick injuries or sexual contact
- Prevention of hepatitis B infection in newborns of mothers carrying hepatitis B
- Prevention after liver transplantation in selected patients
Usual adult dose
Dose depends on exposure and product. Commonly 500–1,000 IU intramuscularly after exposure; transplant regimens are specialist-directed.
Usual dose in children
For newborns, commonly 30–100 IU/kg intramuscularly after birth; other doses depend on age and exposure.
Common side effects
- Injection-site pain or tenderness
- Headache, tiredness, or nausea
- Fever or chills
- Rare severe allergic reaction
Important warnings
- Give as soon as possible after exposure; vaccination is often also needed.
- Do not inject into a vein unless the specific product permits it.
- Use caution with severe immunoglobulin allergy or IgA deficiency.
- May interfere with certain live-virus vaccines, including measles and mumps vaccines.
Pregnancy
May be used when needed; hepatitis B exposure prevention can protect both pregnant person and baby.
Breastfeeding
Generally compatible with breastfeeding; it is an antibody preparation.
Interactions
- May reduce responses to live vaccines; timing may need adjustment.
- Can interfere with some antibody-based laboratory tests.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.