About abiraterone acetate
Androgen biosynthesis inhibitor
Used for
- Treats advanced prostate cancer, usually with other medicines.
- Used with prednisone or prednisolone and hormone therapy.
Usual adult dose
1,000 mg once daily on an empty stomach, with prescribed prednisone or prednisolone; dosing may differ with liver problems.
Common side effects
- High blood pressure, fluid retention, or low potassium.
- Fatigue, joint pain, hot flashes, or diarrhea.
- Liver enzyme changes or liver injury.
Important warnings
- Requires regular blood pressure, potassium, and liver blood tests.
- Can harm an unborn baby; pregnant people should not handle broken tablets.
- Take on an empty stomach; food can greatly increase absorption.
- Do not stop prescribed corticosteroids without medical guidance.
Pregnancy
Not for use during pregnancy; may harm a developing baby. Use effective contraception when relevant.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Strong CYP3A4 inducers, such as rifampin, can lower abiraterone levels.
- May increase effects of medicines affected by CYP2D6 or CYP2C8.
- Some medicines that prolong the QT interval may increase heart rhythm risks, especially with low potassium.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.