About nicorandil
Anti-anginal potassium-channel opener and nitrate
Used for
- Prevention and long-term treatment of angina (chest pain)
- Sometimes used when other anti-anginal medicines are unsuitable or insufficient
Usual adult dose
Usually 10–20 mg twice daily; doses are adjusted to response and tolerability.
Common side effects
- Headache, especially when treatment starts
- Dizziness or weakness
- Flushing
- Nausea or vomiting
Important warnings
- Can cause serious ulcers in the mouth, digestive tract, skin, or eyes.
- Do not use with sildenafil, tadalafil, or vardenafil, or other medicines for erectile dysfunction.
- May cause low blood pressure; risk can increase with alcohol or other blood-pressure medicines.
- Seek urgent assessment for severe or persistent stomach pain, bleeding, or an eye ulcer.
Pregnancy
Safety is not established; use during pregnancy is generally avoided unless clearly necessary.
Breastfeeding
Safety is not established; breastfeeding is generally not recommended during treatment.
Interactions
- Sildenafil, tadalafil, vardenafil, and related medicines can cause a dangerous blood-pressure drop.
- Other blood-pressure-lowering medicines may increase dizziness or low blood pressure.
- Alcohol may worsen blood-pressure lowering.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.