About tenapanor
NHE3 inhibitor; constipation treatment
Used for
- Treats irritable bowel syndrome with constipation in adults.
- Treats chronic idiopathic constipation in adults.
Usual adult dose
50 mg by mouth twice daily, immediately before breakfast and dinner.
Common side effects
- Diarrhea, sometimes severe
- Abdominal pain
- Abdominal swelling
- Gas
Important warnings
- Do not use in children under 6 years; severe dehydration risk.
- Avoid in children aged 6–17 years; safety and effectiveness are unestablished.
- Stop treatment and contact a clinician if severe diarrhea occurs.
- Avoid with suspected or known bowel obstruction.
Pregnancy
Human pregnancy data are limited; absorption is minimal, but use should be assessed by a clinician.
Breastfeeding
It is unknown whether tenapanor enters human milk; discuss use with a clinician.
Interactions
- Other medicines taken by mouth may be absorbed less; separate them by at least one hour before or two hours after tenapanor when appropriate.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.