About glyceryl trinitrate
Organic nitrate vasodilator
Used for
- Relief of pain from chronic anal fissures.
Usual adult dose
Apply a small amount to the anal canal every 12 hours, as prescribed; treatment is usually limited to several weeks.
Common side effects
- Headache
- Dizziness or light-headedness
- Nausea
- Low blood pressure
Important warnings
- Can cause severe dizziness or fainting from low blood pressure.
- Do not use with sildenafil, tadalafil, vardenafil, or riociguat.
- Avoid alcohol, which can worsen low blood pressure.
- Use only as directed; excessive use can cause serious harm.
Pregnancy
Safety is not well established; use only if a clinician considers it necessary.
Breastfeeding
Safety is not well established; seek clinical guidance before use.
Interactions
- Sildenafil, tadalafil, and vardenafil can cause a dangerous blood-pressure drop.
- Riociguat can cause a dangerous blood-pressure drop.
- Other nitrates or blood-pressure-lowering medicines may increase dizziness or fainting.
- Alcohol may worsen low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.