About timolol maleate + brimonidine tartrate
Ophthalmic alpha-2 agonist and beta blocker
Used for
- Reduces raised eye pressure in open-angle glaucoma or ocular hypertension
Usual adult dose
One drop in the affected eye(s) twice daily, about 12 hours apart.
Usual dose in children
Not recommended for children under 2 years; dosing for older children is specialist-directed.
Common side effects
- Eye redness, burning, stinging, or itching
- Dry eyes or blurred vision
- Sleepiness, fatigue, or headache
- Slow heart rate or low blood pressure
Important warnings
- Can worsen asthma, severe chronic lung disease, slow heartbeat, or heart block.
- May cause drowsiness and lower blood pressure; use caution with driving.
- Remove contact lenses before use; wait at least 15 minutes before reinserting.
- Press the inner corner of the eye after drops to reduce absorption into the body.
Pregnancy
Use only if clearly needed; safety information is limited. Timolol may affect the fetus, especially late in pregnancy.
Breastfeeding
Timolol and brimonidine may pass into breast milk; brimonidine is not recommended while breastfeeding.
Interactions
- Other beta blockers or blood-pressure medicines may increase slow heartbeat or low blood pressure.
- Medicines that slow heart rate, such as digoxin, may increase cardiac effects.
- MAO inhibitors and some antidepressants may alter brimonidine effects.
- Sedatives and alcohol may increase drowsiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.