About estradiol valerate
Estrogen hormone
Used for
- Treats symptoms of menopause, such as hot flashes and vaginal dryness
- Treats low estrogen due to ovarian failure or removal
- Used with other medicines in some fertility treatments
Usual adult dose
Menopause symptoms: usually 1–2 mg by mouth daily, adjusted to symptoms. Dose depends on the condition.
Common side effects
- Breast tenderness
- Headache
- Nausea
- Irregular vaginal bleeding
Important warnings
- If the uterus is present, a progestogen is usually needed to reduce endometrial cancer risk.
- Estrogen can increase risks of blood clots, stroke, and certain cancers.
- Not for preventing heart disease or dementia.
- Unexplained vaginal bleeding needs assessment before use.
Pregnancy
Not used during pregnancy; stop if pregnancy occurs.
Breastfeeding
May reduce milk supply; use requires clinician guidance.
Interactions
- Some seizure medicines and rifampin can reduce estrogen effects.
- St. John’s wort may reduce estrogen levels.
- Estrogen can affect thyroid replacement requirements.
- Some medicines may raise estrogen levels or side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.