About quetiapine fumarate
Atypical antipsychotic
Used for
- Schizophrenia
- Bipolar disorder, including manic and depressive episodes
- Add-on treatment for major depressive disorder in some countries
Usual adult dose
Varies by condition and formulation; commonly titrated to 150–800 mg daily, usually in divided doses or once daily.
Common side effects
- Sleepiness and dizziness
- Dry mouth and constipation
- Weight gain and increased appetite
- Low blood pressure on standing
Important warnings
- May increase risk of death in older adults with dementia-related psychosis.
- Can raise blood sugar and cholesterol; weight and metabolic checks may be needed.
- Can cause movement problems, low white blood cells, or abnormal heart rhythm.
- Do not stop suddenly; dose may need gradual reduction.
Pregnancy
Use only after weighing potential benefits and risks; late-pregnancy use may cause newborn withdrawal or movement symptoms.
Breastfeeding
Quetiapine passes into breast milk in small amounts; monitor the infant for unusual sleepiness or poor feeding.
Interactions
- Alcohol and sedating medicines can worsen sleepiness.
- Strong CYP3A4 inhibitors, such as ketoconazole, can raise quetiapine levels.
- Strong CYP3A4 inducers, such as carbamazepine, can lower quetiapine levels.
- May enhance low blood pressure from some medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.